Obtaining a complete good-quality sequence and annotation for the long double-stranded DNA genome of the African swine fever virus (ASFV) from next-generation sequencing (NGS) technology has proven difficult, despite the increasing availability of reference genome sequences and the increasing affordability of NGS. A gap analysis conducted by the global African swine fever research alliance (GARA) partners identified that a standardized, automatic pipeline for NGS analysis was urgently needed, particularly for new outbreak strains. Whilst there are several diagnostic and research labs worldwide that collect isolates of the ASFV from outbreaks, many do not have the capability to analyze, annotate, and format NGS data from outbreaks for submission to NCBI, and some publicly available ASFV genomes have missing or incorrect annotations.
View Article and Find Full Text PDFBackground: There is overwhelming evidence for the preventive effects of regular physical activity and healthy eating habits on the risk for developing a non-communicable disease (NCD). Increasing attention has been paid to community-wide approaches in the battle against NCDs. Communities can create supportive policies, modify physical environments, and foster local stakeholder engagement through intersectoral collaboration to encourage communities to support healthy lifestyles.
View Article and Find Full Text PDFMaterials (Basel)
March 2023
This paper studies the properties of the Preisach model and the play model, and compare their similarities. Both are history-dependent hysteresis models that are used to model magnetic hysteresis. They are described as discrete sums of simple hysteresis operators but can easily be reformulated as integral equations of continuous distribution functions using either a Preisach weight distribution function or a play distribution function.
View Article and Find Full Text PDFAn outbreak of disease in a Swedish beef cattle herd initiated an in-depth study to investigate the presence of bacteria and viruses in the blood of clinically healthy ( = 10) and clinically diseased cattle ( = 20) using whole-genome shotgun sequencing (WGSS). The occurrence of infectious agents was also investigated in ticks found attached to healthy cattle ( = 61) and wild deer (n = 23), and in spleen samples from wild deer ( = 30) and wild boars ( = 10). Moreover, blood samples from 84 clinically healthy young stock were analysed for antibodies against and The WGSS revealed the presence of at least three distinct variants that were most closely related to .
View Article and Find Full Text PDFIn November 2016, infectious pancreatic necrosis virus (IPNV) was isolated from a broodstock female of landlocked sea trout () in Lake Vänern in Sweden. VP2 gene sequencing placed the IPNV isolate in genogroup 6, for which pathogenicity is largely unknown. Lake Vänern hosts landlocked sea trout and salmon populations that are endangered, and thus the introduction of new pathogens poses a major threat.
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