Population-based randomized trial of screening for clinically significant prostate cancer ProScreen: a pilot study.

Objectives: To evaluate the feasibility of a population-based screening trial using prostate-specific antigen (PSA), a kallikrein panel and multiparametric magnetic resonance imaging (MRI) aimed at minimizing overdiagnosis, while retaining mortality benefit.

Patients And Methods: Feasibility of the screening algorithm was evaluated in terms of participation, screening test results and cancer detection. A random sample of 400 men aged 65 years was identified from the population registry and invited for screening with three stepwise tests (PSA, kallikrein panel and MRI).

Primary aortoduodenal fistula: successful grafting with axillo-bifemoral bypass.

Primary aortoduodenal fistula (PADF) is uncommon direct pathological communication between the abdominal aorta and duodenum, which may cause life-threatening gastrointestinal bleeding. PADF leads to high mortality and morbidity unless it is promptly evaluated and appropriate surgical intervention performed. We present a case report describing PADF treated successfully with axillobifemoral bypass.