Publications by authors named "M Leali"
Article Synopsis
- Measuring deeply virtual Compton scattering (DVCS) on the neutron is essential for understanding the nucleon's structure through generalized parton distributions (GPDs).
- Neutron targets help complement data obtained from polarized protons, particularly in determining the poorly understood GPD E, which is crucial for analyzing quark contributions to nucleon spin.
- The experiment utilized a longitudinally polarized electron beam at Jefferson Lab and the CLAS12 detector to measure DVCS on the neutron for the first time, providing new insights into quark-flavor separation of relevant Compton form factors.
Antiproton annihilation at rest in thin solid targets and comparison with Monte Carlo simulations.
Eur Phys J A Hadron Nucl
November 2024
The mechanism of antiproton-nucleus annihilation at rest is not fully understood, despite substantial previous experimental and theoretical work. In this study we used slow extracted antiprotons from the ASACUSA apparatus at CERN to measure the charged particle multiplicities and their energy deposits from antiproton annihilations at rest on three different nuclei: carbon, molybdenum and gold. The results are compared with predictions from different models in the simulation tools Geant4 and FLUKA.
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- The study aimed to compare the effects of personalized positive end-expiratory pressure (PEEP) versus a standard low PEEP/FiO2 table on patients with acute respiratory distress syndrome (ARDS) undergoing pressure support ventilation (PSV).
- Researchers conducted a cross-over randomized trial with 30 ARDS patients, measuring how different PEEP settings affected lung mechanics and patient comfort.
- Results showed that the personalized PEEP significantly improved lung function, reduced respiratory effort, and did not lead to lung overdistension, making it a promising approach for treating ARDS during ventilation.
Objectives: Pulmonary ventilation/perfusion (V/Q) mismatch measured by electrical impedance tomography (EIT) is associated with the outcome of patients with the acute respiratory distress syndrome (ARDS), but the underlying pathophysiological mechanisms have not been fully elucidated. The present study aimed to verify the correlation between relevant pathophysiological markers of ARDS severity and V/Q mismatch.
Design: Prospective observational study.
Patient self-inflicted lung injury (P-SILI) is a major challenge for the ICU physician: although spontaneous breathing is associated with physiological benefits, in patients with acute respiratory distress syndrome (ARDS), the risk of uncontrolled inspiratory effort leading to additional injury needs to be assessed to avoid delayed intubation and increased mortality. In the present review, we analyze the available clinical and experimental evidence supporting the existence of lung injury caused by uncontrolled high inspiratory effort, we discuss the pathophysiological mechanisms by which increased effort causes P-SILI, and, finally, we consider the measurements and interpretation of bedside physiological measures of increased drive that should alert the clinician. The data presented in this review could help to recognize injurious respiratory patterns that may trigger P-SILI and to prevent it.
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