Publications by authors named "M Le Cause"

This review focuses on the prognostic role of resting-state functional magnetic resonance imaging (fMRI) in disorders of consciousness (DOCs). Several studies were conducted to determine the diagnostic accuracy in DOC patients to identify prognostic markers and to understand the neural correlates of consciousness. A correct diagnosis of consciousness in unresponsive or minimally responsive patients is important for prognostic and therapeutic management.

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Patients with Autism Spectrum Disorder (ASD) need to be provided with behavioral, psychological, educational, or skill-building interventions as early as possible. Cognitive Behavior Therapy has proven useful to manage such problems. There is also growing evidence on the usefulness of Virtual Reality Therapy (VRT) in treating various functional deficits in ASD.

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The pathophysiology of chronic tic disorder (cTD) and Gilles de la Tourette syndrome (GTS) is characterized by the dysfunction of both motor and non - motor cortico - striatal - thalamo - cortical (CSTC) circuitries, which leads to tic release and comorbids. A role of fronto - parietal network (FPN) connectivity breakdown has been postulated for tic pathogenesis, given that the FPN entertain connections with limbic, paralimbic, and CSTC networks. Our study was aimed at characterizing the FPN functional connectivity in cTD and GTS in order to assess the role of its deterioration in tic severity and the degree of comorbids.

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Article Synopsis
  • Autism Spectrum Disorders (ASDs) are developmental disorders that impact communication and behavior, with a global prevalence of about 1%, and a higher occurrence in males compared to females.
  • Traditional treatments primarily involve cognitive-behavioral therapy (CBT) through direct interaction with therapists, but recent advancements have incorporated virtual reality (VR) into cognitive treatment for ASDs.
  • A study involving a 16-year-old boy with severe ASD showed that combining VR with CBT led to better improvements in attention and spatial cognition compared to CBT alone, suggesting VR can be an effective tool in enhancing cognitive functions for those with severe ASD.
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Adolescents having moderate to severe traumatic brain injury (TBI) often experience long-lasting cognitive, emotional, and behavioral problems. In current clinical practice, rehabilitation techniques to treat cognitive abnormalities may be classified in two main categories, i.e.

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