Publications by authors named "M Laurens"
Background: External lumbar drainage (ELD) of cerebrospinal fluid may help control intracranial pressure following a traumatic brain injury. We aimed to assess the efficacy and safety of ELD in post-traumatic intracranial hypertension (IH).
Methods: This retrospective monocentric cohort study was conducted in the trauma critical care unit of the regional Level-I trauma centre between January 2012 and December 2022.
Article Synopsis
- Vaccine safety and immunogenicity data are crucial for making informed decisions in countries where both HIV and typhoid are prevalent, specifically focusing on HIV-exposed uninfected (HEU) children.
- In a study involving Malawian infants, HEU and HIV unexposed uninfected (HUU) participants received the Vi-tetanus toxoid conjugate vaccine (Vi-TT) at different ages, with safety and immune response monitored after vaccination.
- Results showed that the vaccine was generally safe with mild adverse events, and both HEU and HUU children had strong immune responses, indicating that a single dose of Vi-TT could be effectively introduced in HIV-endemic regions.
Children with hemoglobin AC or AS have decreased susceptibility to clinical malaria. Parasite variant surface antigen (VSA) presentation on the surface of infected erythrocytes is altered in erythrocytes with hemoglobin C (Hb AC) or sickle trait (Hb AS) mutations in vitro. The protective role of incomplete or altered VSA presentation against clinical malaria in individuals with Hb AC or AS is unclear.
View Article and Find Full Text PDFUnlabelled: parasites, the causative organism of malaria, caused over 600,000 deaths in 2022. In Mali, causes the majority of malaria cases and deaths and is transmitted seasonally. Anti-malarial immunity develops slowly over repeated exposures to and some aspects of this immunity (e.
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