Publications by authors named "M Laura Migliori"
Importance: A diverse ophthalmic workforce is key to equitable care, and identifying areas of underrepresentation is important in tackling vision care disparities.
Objective: To evaluate the diversity of applicants and matriculants in ophthalmology residency programs relative to medical school graduates and analyze the intersection of race and gender within this pathway.
Design, Setting, And Participants: This retrospective cross-sectional study conducted from 2022 to 2024 used representation quotients (RQs) using reports from the Association of University Professors of Ophthalmology and San Francisco Match, along with demographic data from the Association of American Medical Colleges from 2008 to 2021.
Exploring the Common Mutational Landscape in Cutaneous Melanoma and Pancreatic Cancer.
Pigment Cell Melanoma Res
January 2025
Cutaneous melanoma (CM) and pancreatic cancer are aggressive tumors whose incidences are rapidly increasing in the last years. This review aims to provide a complete and update description about mutational landscape in CM and pancreatic cancer, focusing on similarities of these two apparently so different tumors in terms of site, type of cell involved, and embryonic origin. The familial forms of CM and pancreatic cancers are often characterized by a common mutated gene, namely CDKN2A.
View Article and Find Full Text PDFIn this study, we assessed the quantity, strength, and acidity of zeolite composites comprising Silicalite-1 grown on ZSM-5 crystals using a combination of infrared (IR) and solid-state nuclear magnetic resonance (NMR) spectroscopy. The composites were created through the direct growth of Silicalite-1 crystals on ZSM-5 (P_ZSM-5), either with or without the organic structure-directing agent (OSDA) introduced into the ZSM-5 channels (samples: H_ZSM-5_Sil1 and TPA_ZSM-5_Sil1). The results revealed that Silicalite-1 grew differently when the ZSM-5 core was in the H form (empty pores) compared to when the OSDA was still present in the sample.
View Article and Find Full Text PDFArticle Synopsis
- High volume hemofiltration (HVHF) aimed to remove inflammatory substances linked to kidney injury from sepsis, but recent trials showed no improvement in patient outcomes compared to standard volume hemofiltration (SVHF).
- This study investigated the effects of plasma from patients treated with HVHF or SVHF on various cell types related to inflammation and injury, focusing on leukocyte adhesion and cell damage over time.
- Findings indicated that while both HVHF and SVHF reduced inflammatory markers temporarily, they did not differ significantly, and septic plasma consistently caused harmful effects on endothelial and tubular epithelial cells, indicating ongoing microvascular injury.
Article Synopsis
- Zeolites are crystalline materials with tiny pores used in catalysis, but their effectiveness can be hampered by strong acid sites on their surfaces.
- Recent strategies focus on neutralizing these external acid sites to enhance selectivity and reduce unwanted reactions, like coke formation.
- This Mini-Review summarizes various techniques for passivating these strong acid sites, such as chemical treatments and silicate deposition, and discusses their impact on zeolites' catalytic performance.