Publications by authors named "M Lanz"
Satiety-enhancing placebo intervention decreases selective attention to food cues.
Front Psychiatry
December 2024
Background: As placebo interventions could influence appetite and satiety in first studies, they are a promising tool for the future treatment of obesity. Furthermore, individuals with heightened body weight show increased selective attention for food cues. This study aimed to investigate whether placebo induced changes of appetite and satiety can affect attention allocation and to examine correlating factors.
View Article and Find Full Text PDFDefining the cellular factors that drive growth rate and proteome composition is essential for understanding and manipulating cellular systems. In bacteria, ribosome concentration is known to be a constraining factor of cell growth rate, while gene concentration is usually assumed not to be limiting. Here, using single-molecule tracking, quantitative single-cell microscopy, and modeling, we show that genome dilution in cells arrested for DNA replication limits total RNA polymerase activity within physiological cell sizes across tested nutrient conditions.
View Article and Find Full Text PDFBackground: Asthma in children is a leading cause of missed school days, emergency department visits, and hospitalizations. Approximately 40% of children with asthma experience uncontrolled disease and annual exacerbations. There is a need for a validated composite tool for children, such as the Asthma Impairment and Risk Questionnaire (AIRQ), which was developed to assess current control and predict exacerbations in adolescents and adults with asthma.
View Article and Find Full Text PDFArticle Synopsis
- Diffusion of macromolecules in the cytoplasm is crucial for cellular processes, but how it's regulated based on cell size is not well understood.
- Researchers studied how the size of fission yeast cells influences the diffusion of genetically-encoded 40 nm nanoparticles (cytGEMs) within the cytoplasm.
- Their findings revealed that smaller cells have decreased diffusion coefficients for cytGEMs, while larger cells show increased diffusion, potentially due to differences in DNA-to-cytoplasm ratio and specific changes in cell proteomes based on size.
Article Synopsis
- The study investigates the use of short-acting ß-agonist (SABA) and maintenance therapy in patients with mild persistent asthma who experienced serious exacerbations, categorized as hospital visits or urgent care needs.
- Analyzed data from over 323,000 asthma patients from 2010 to 2017 revealed that prior to serious exacerbations, more patients filled SABA prescriptions compared to maintenance therapy, but after the event, they shifted to filling maintenance medications more frequently.
- The findings suggest a potential "window of opportunity" to improve treatment strategies for preventing serious exacerbations by timely adjusting medication types before and after such events.