Objective: To determine the relationship between insulin resistance (IR) and atheroma burden in Pakistanis.
Methods: A prospective case-control study of 400 patients selected for the presence/absence of angiographic disease. Coronary atheroma burden was quantified and IR and cardiovascular risk factors were measured.
Background: Metabolic syndrome (M-IRS) is common in Asians. This study investigated the relationship of two definitions of M-IRS to atherosclerosis in Indian Asians with suspected coronary arterial disease (CAD).
Methods: 400 patients with chest pain selected for the presence or absence of angiographic disease were recruited from a tertiary referral centre in Pakistan into a prospective case-control study.
Background: Erectile dysfunction is related to endothelial function. Cardiovascular risk factors determine endothelial function. Sildenafil is effective in treatment of erectile dysfunction but shows variable results.
View Article and Find Full Text PDFObjective: To investigate the relationship of creatinine and calculated glomerular filtration rate (GFR) with coronary arterial disease (CAD) in Pakistani patients.
Subjects: Four hundred individuals with chest pain; 200 with angiographic disease matched with 200 without occlusive disease.
Design: A prospective case-control study.
Background: Erectile dysfunction is related to penile arterial endothelial nitric oxide production. Asymmetric dimethylarginine (ADMA) and E-selectin are often considered plasma markers of endothelial function.
Objective: This study investigated the relationship between these plasma markers and cardiovascular risk factors in patients with erectile dysfunction.