Linking structural and functional changes during healthy aging and semantic dementia using multilayer brain network analysis.

Healthy aging is characterized by frontal and diffuse brain changes, while certain age-related pathologies such as semantic dementia will be associated with more focal brain lesions, particularly in the temporo-parietal regions. These changes in structural integrity could influence functional brain networks. Here we use multilayer brain network analysis on structural (DWI) and functional (fMRI) data in younger and older healthy individuals and patients with semantic dementia.

Narration of a collective traumatic event according to the presence of PTSD and considering the social function.

Introduction: Individuals suffering from PTSD recount the traumatic event using perceptual, emotional and sensory details. Memorization and recall of individual events are influenced by the individual's social function, i.e.

MEM&SO protocol: understanding the determinants of social learning in neurodegenerative diseases.

Background: People with neurodegenerative diseases may have difficulty learning new information, owing to their cognitive impairments. Teaching them techniques for learning in social contexts could alleviate this difficulty. The present study will examine the performances of patients with Alzheimer's disease and patients with the semantic variant of primary progressive aphasia on a memory test administered in three social contexts.

[Memory tests].

MEMORY TESTS. Memory tests used in clinical practice mainly concern anterograde memory through the evaluation of learning, short- or long-term retention, and retrieval of information. They use different types of material (verbal or visual) and different tasks to assess the integrity of the different memory processes: encoding, storage and retrieval.

[Memory alterations in post-traumatic stress disorder].

Post-Traumatic Stress Disorder (PTSD) is a disorder that develops following the experience of a highly stressful event, which involves a confrontation with death or the threat of death, serious injury or sexual violence. It is characterized by symptoms such as intrusions, avoidance and hypervigilance. According to the literature, PTSD is associated with an imbalance between a privileged memorization of the emotional and sensory aspects of the traumatic event and a failure to memorize the contextual aspects.