Publications by authors named "M Laino"
Background: Intrahepatic cholangiocarcinoma (ICC) is an aggressive disease with increasing incidence and its genetic alterations could be the target of systemic therapies.
Aims: To elucidate if radiomics extracted from computed tomography (CT) may non-invasively predict ICC genetic alterations.
Methods: All consecutive patients with a diagnosis of a mass-forming ICC (01/2016-06/2022) were considered.
Background: The emergence of pyrethroid resistance has threatened the elimination of Triatoma infestans from the Gran Chaco ecoregion. We investigated the status and spatial distribution of house infestation with T. infestans and its main determinants in Castelli, a municipality of the Argentine Chaco with record levels of triatomine pyrethroid resistance, persistent infestation over 2005-2014, and limited or no control actions over 2015-2020.
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- This systematic review assesses the effectiveness of radiomics for noninvasively determining isocitrate dehydrogenase (IDH) status in grade 4 and lower-grade diffuse gliomas through a meta-analysis of 26 studies involving 3,280 patients.
- The pooled sensitivity and specificity for detecting IDH mutations were found to be 79% and 80%, indicating good accuracy, but the overall study quality was low, raising concerns about potential bias.
- Subgroup analyses revealed that lower-quality studies had a lower rate of false positives, and there were no significant differences in accuracy between grade 4 and lower-grade tumors or between studies using single versus multiple imaging sequences.
Background: No quantitative computed tomography (CT) biomarker is actually sufficiently accurate to assess Crohn's disease (CD) lesion activity, with adequate precision to guide clinical decisions.
Purpose: To assess the available literature on the use of iodine concentration (IC), from multi-spectral CT acquisition, as a quantitative parameter able to distinguish healthy from affected bowel and assess CD bowel activity and heterogeneity of activity along the involved segments.
Material And Methods: A literature search was conducted to identify original research studies published up to February 2022.