Publications by authors named "M Lacko"
Objectives: The aim of this study was the evaluation of a group of patients treated at the Department of Orthopaedics and Traumatology of Locomotory Apparatus at Luis Pasteur University Hospital in Košice for septic arthritis in relation to risk factors and chronic diseases and its microbial aetiologic profile.
Methods: We conducted a retrospective study of patients including all episodes of septic arthritis from March 2013 to August 2022. The occurrence of chronic diseases, risk factors and its microbiological profile were investigated.
Article Synopsis
- Osteoarthritis (OA) is common and currently lacks effective treatments that can both modulate the immune response and repair cartilage, prompting research into extracellular vesicles (EVs) from blood-derived products like platelet poor plasma (PPP).
- This study examined how PPP-derived EVs affect OA chondrocytes in a lab setting, revealing that these EVs possess anti-inflammatory properties and can significantly reduce the expression of certain inflammatory genes associated with OA.
- The findings suggest that PPP-EVs can potentially be developed as a new type of treatment for OA, offering promise for better management of the disease in the future.
Background: There is no consensus regarding the indication for postoperative radiotherapy (PORT) for T1- and T2-classified squamous cell carcinoma (SCC) of the external auditory canal (EAC) even with negative surgical margins. This study aimed to evaluate whether PORT provides additional benefits for these cases.
Methods: We collected retrospective data from fourteen international hospitals, including resected pT1- and pT2-classified EAC SCC with negative surgical margins.
Introduction: The study aims were: (1) to assess the incidence in 1 year, the cumulative incidences and the period prevalence in 3/5 years of the condition of patients accruing cumulative effective dose (CED) ≥ 100 mSv in health care centres providing CT examinations in Slovakia; and (2) to quantify their variability among different centres, to test the feasibility of establishing recurrent exposure reference levels (RERL) on a nationwide level.
Materials And Methods: The data were tracked during five consecutive years using the CT dose index and dose-length-product along with the patient's ID. ED was calculated using conversion factors.
Aim Of The Study: To investigate the relationship between serum lipoprotein (a) [Lp(a)] concentration and the risk of ischaemic stroke (IS) and its subtypes.
Clinical Rationale For The Study: Lp(a) plays a role in atherogenic, pro-thrombotic, and antifibrinolytic processes. Elevated plasma Lp(a) is a strong independent risk factor for the development and progression of atherosclerotic disease.