Publications by authors named "M La Grua"

Article Synopsis
  • - The study investigates the effectiveness of combining high molecular weight hyaluronic acid (HMWHA) and collagen tripeptide (CTP) to treat patients with both osteoarthritis (OA) and calcium pyrophosphate deposition (CPPD), conditions that worsen inflammation and cartilage damage.
  • - A retrospective analysis monitored 29 patients receiving ultrasound-guided injections, measuring pain and joint function over 6 months using NRS and WOMAC scores, revealing significant improvement in both assessments.
  • - Results indicated that 79% of patients experienced meaningful pain reduction (NRS) and 83% showed functional improvement (WOMAC), with the most notable benefits observed by the 6-month evaluation.
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Introduction: Scientific data about neurophysiological changes subsequent to pulsed radiofrequency (PRF) are still lacking. The goal of this study was to evaluate sural nerve conduction and Hoffmann reflex (H-reflex) in soleus muscle following adhesiolysis and PRF in patients with unilateral chronic lumbosacral L5-S1 neuropathic radiating pain.

Methods: Seventeen patients received two cycles of 240 seconds high-voltage PRF and epidural adhesiolysis.

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Objectives: Despite the interest in scientific community, there is still poor evidence about pulsed radiofrequency (PRF) efficacy in the treatment of neuropathic pain. In order to determine whether high-voltage PRF and epidural adhesiolysis (PRF-EA) showed better results than epidural adhesiolysis alone (EA), a randomized, double-blind, comparative-effectiveness study was conducted in patients with chronic lumbosacral radiating pain and neuropathic features.

Materials And Methods: A total of 41 patients were randomly allocated to 2 groups.

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Purpose: Management of patients with persisting pain after spine surgery (PPSS) shows significant variability, and there is limited evidence from clinical studies to support treatment choice in daily practice. This study aimed to develop patient-specific recommendations on the management of PPSS.

Methods: Using the RAND/UCLA appropriateness method (RUAM), an international panel of 6 neurosurgeons, 6 pain specialists, and 6 orthopaedic surgeons assessed the appropriateness of 4 treatment options (conservative, minimally invasive, neurostimulation, and re-operation) for 210 clinical scenarios.

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