Publications by authors named "M L Stromillo"
Article Synopsis
- The study investigates the effects of discontinuing dimethyl fumarate (DMF) during early pregnancy in women with multiple sclerosis (MS), analyzing 137 pregnancies from Italian MS Centers.
- Results show that disease activity typically decreases during pregnancy but increases postpartum; higher relapse rates before conception correlate with faster relapses after giving birth.
- Importantly, DMF exposure during early pregnancy did not negatively affect fetal outcomes, suggesting it is safe for the pregnancy context.
Background: Research work has shown that hippocampal subfields are atrophic to varying extents in multiple sclerosis (MS) patients. However, studies examining the functional implications of subfield-specific hippocampal damage in early MS are limited. We aim to gain insights into the relationship between hippocampal atrophy and memory function by investigating the correlation between global and regional hippocampal atrophy and memory performance in early MS patients.
View Article and Find Full Text PDFChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis.
Elisabetta Maida Marcello Moccia Raffaele Palladino Giovanna Borriello Giuseppina Affinito Maria Laura Stromillo
J Neurol
July 2024
Article Synopsis
- A study was conducted to compare the empathy and satisfaction levels of people with Multiple Sclerosis (PwMS) towards responses from neurologists versus ChatGPT for common questions.
- The results showed that ChatGPT's responses were perceived as more empathetic than those from neurologists, although no significant difference in overall satisfaction was found.
- The study suggests that while AI like ChatGPT can enhance patient interactions, physicians need to adapt to digital advancements and guide patients in effectively using AI tools in healthcare.
Article Synopsis
- This study investigated cortical demyelination and remyelination in 140 MS patients over 5 years using magnetization transfer imaging (MTI), revealing significant changes in myelin content.
- Results showed that the degree of cortical demyelination was associated with increased cortical atrophy and clinical progression, regardless of age or MS type.
- Although remyelination occurred in many patients, it was less successful near cerebrospinal fluid (CSF) areas, indicating that effective repair processes may not fully prevent disease progression.
Article Synopsis
- Cognitive impairment is prevalent among people with multiple sclerosis (PwMS) and significantly affects their quality of life, making cognitive assessment crucial for treatment and understanding disease progress.
- The study aimed to update normative data for the Brief Repeatable Battery of Neuropsychological Tests (BRB-N) version A in the Italian population by analyzing data from 342 healthy subjects across four Italian sites.
- The results indicate no major demographic differences among the sites, and they established updated z-scores that enhance the reliability of cognitive assessments for PwMS and other clinical groups in Italy.