Publications by authors named "M L Schiavinato"

Dealing with infections is a daily challenge for wild animals. Empirical data show an increase in reactive oxygen species (ROS) production during immune response. This could have consequences on telomere length, the end parts of linear chromosomes, commonly used as proxy for good health and ageing.

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Article Synopsis
  • - The study focuses on improving the production of antibody fragments (Fabs) in E. coli, specifically analyzing the responses of two strains, BL21(DE3) and HMS174(DE3), during the expression of different Fabs using RNA sequencing.
  • - Findings showed that the production of Fabx negatively impacted cell growth more than FTN2, with RNA-seq revealing stress responses related to protein aggregation and cell envelope integrity, alongside nutrient depletion during the cultivation process.
  • - The research identified ribosome stalling as a key factor contributing to low yields of Fabx and demonstrated that modifying the amino acid sequence could enhance production, along with unexpected differences in gene expression responses between the two E. coli strains.
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Heterozygosity is a genetic condition in which two or more alleles are found at a genomic locus. Individuals that are the offspring of genetically divergent yet still interfertile parents (e.g.

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Theoretical models indicate that the evolution of biparental care depends on how parents behaviourally negotiate their level of care in response to those of their partner and whether sexes and individuals consistently vary in their response (compensatory response). While the compensatory response has been widely investigated empirically, its repeatability has rarely been assessed. In this study, we used a reaction norm approach to investigate the repeatability of the compensatory offspring provisioning of a parent after temporary removal of its partner in the pied flycatcher () across different breeding seasons and partners.

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Background: There is growing interest in understanding gut microbiome dynamics, to increase the sustainability of livestock production systems and to better understand the dynamics that regulate antibiotic resistance genes (, the resistome). High-throughput sequencing of RNA transcripts (RNA-seq) from microbial communities (metatranscriptome) allows an unprecedented opportunity to analyze the functional and taxonomical dynamics of the expressed microbiome and emerges as a highly informative approach. However, the isolation and preservation of high-quality RNA from livestock fecal samples remains highly challenging.

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