Biological activity of some derivatives of β-cyclodextrin.

New compounds of β-cyclodextrin containing covalently bound (conjugated) residues of acetylsalicylic and 1-(4-isobutylphenyl)-propionic acids were synthesized in the reaction of chlorides of the corresponding acids with β-cyclodextrin. We studied antiplatelet and antiphlogistic properties of these substances. It was shown that new compounds are comparable and in some cases are superior to the reference drugs acetylsalicylic acid and ibuprofen by anti-inflammatory and antiaggregant activities.

[Action motor food of behaviour in modular device].

The technique for studying of the got behaviour at laboratory animals is offered. The corrective influence of high doses of Piracetam is shown on the example of aimed motor food runnings which contribute to food reguiments. Primary differences of the modular device in comparison with the "Colombian" chamber are noted.