Background: Chronic postsurgical pain (CPSP) persists beyond the expected healing period after surgery, imposing a substantial burden on overall patient well-being. Unfortunately, CPSP often remains underdiagnosed and undertreated. To better understand the mechanism of CPSP development, we aimed to identify genetic variants associated with CPSP.
View Article and Find Full Text PDFBackground: It is not yet clear to what extent the physiologic regulatory mechanisms that maintain core body temperature are reflected by changes in resting energy expenditure (REE). Particularly, in indirect calorimetry with a canopy, the effects of short-term temperature exposures have not yet been investigated. This can be of relevance for the determination of REE in practice.
View Article and Find Full Text PDFJ Neurol Neurosurg Psychiatry
January 2025
Background: White matter hyperintensities (WMH) have been implicated in the pathogenesis of neuropsychiatric symptoms of dementia but the functional significance of WMH in specific white matter (WM) tracts is unclear. We investigate whether WMH burden within major WM fibre classes and individual WM tracts are differentially associated with different neuropsychiatric syndromes in a large multicentre study.
Method: Neuroimaging and neuropsychiatric data of seven memory clinic cohorts through the Meta VCI Map consortium were harmonised.
Introduction: Chronic pain is one of the most common and severe complications after surgery, affecting quality of life and overall wellbeing of patients. Several risk factors have been identified but the mechanisms of chronic postsurgical pain development remain unclear. This study aimed to identify single-nucleotide polymorphisms associated with developing chronic postsurgical pain after abdominal surgery, one of the most common types of surgery.
View Article and Find Full Text PDFWorldwide, the number and proportion of people living in cities continue to grow. Building new districts creates opportunities for designing urban environments that promote the health of their residents from the get-go. In this study, we used the photovoice methodology to explore the perspectives of adolescents on health and well-being in a new urban development area in Munich, Germany.
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