Publications by authors named "M L Nere"
Article Synopsis
- Surveillance of Transmitted Drug Resistance (TDR) is essential for understanding the changes in HIV trends, with a focus on multiple types of antiretroviral drugs and new treatments.
- A study involving 85 individuals diagnosed with primary HIV-1 infection (PHI) from 2020 to 2023 analyzed genetic sequences to identify TDR and its impact on drug resistance, revealing varying levels of resistance to several drug classes.
- The findings highlight the importance of monitoring TDR at the onset of HIV infection to improve treatment strategies and the effectiveness of pre-exposure prophylaxis (PrEP) with newer drug options.
Article Synopsis
- Predicting COVID-19 severity is challenging, but Torque teno virus (TTV) may help assess infection outcomes as a marker of immunity, especially in transplant patients.
- A study at Saint-Louis Hospital in Paris analyzed TTV levels in nasopharyngeal samples from 295 COVID-19 patients and found higher TTV levels in those admitted to the ICU compared to those discharged or in medical wards.
- Elevated TTV loads, specifically above a threshold of 2.91 log copies/mL, were identified as significant predictors of ICU admission, indicating a potential link between TTV levels and respiratory immune response in infected patients.
Background: Among kidney transplant recipients (KTR) with BK virus associated nephropathy (BKVN), BKV genotypes' evolution and anti-BKV humoral response are not well established. We aim to analyze BKV replication and genetic evolution following transplantation, and characterize concomitant anti-BKV-VP1 humoral response.
Methods: We retrospectively analyzed 32 cases of biopsy-proven BKVN.
Background: Mass indoor gatherings were banned in early 2020 to prevent the spread of SARS-CoV-2. We aimed to assess, under controlled conditions, whether infection rates among attendees at a large, indoor gathering event would be similar to those in non-attendees, given implementation of a comprehensive prevention strategy including antigen-screening within 3 days, medical mask wearing, and optimised ventilation.
Methods: The non-inferiority, prospective, open-label, randomised, controlled SPRING trial was done on attendees at a live indoor concert held in the Accor Arena on May 29, 2021 in Paris, France.