Publications by authors named "M L Navarro-Gomez"
The AEP 2025 Vaccination and Immunization Schedule recommended for children, adolescents and pregnant women residing in Spain features the following novelties: Due to the increase in measles cases and outbreaks in recent years, we recommend advancing the second dose of measles, mumps and rubella (MMR) vaccine to 2 years of age. As a consequence of the above, since many autonomous communities (ACs) use the quadrivalent vaccine for the second dose of MMR and varicella vaccines, we recommend, for all ACs, advancing the second dose of varicella vaccine to 2 years of age. Due to the very significant increase in cases of pertussis since late 2023 and especially in 2024, we recommend advancing the dose of Tdap given in adolescence to 10-12 years of age.
View Article and Find Full Text PDFObesity and iron deficiency (ID) are widespread health issues, with subclinical inflammation in obesity potentially contributing to ID through unclear mechanisms. The aim of the present work was to elucidate how obesity-associated inflammation disturb iron metabolism and to investigate the effect of intravenous (IV) iron supplementation on absolute iron deficient pre-obese (BMI 25.0-29.
View Article and Find Full Text PDFExperience of the national cohort of pregnant women with HIV and their children in Spain: temporal trends in vertical transmission of HIV and associated infections.
An Pediatr (Engl Ed)
October 2024
Article Synopsis
- The vertical transmission rate (VTR) of HIV in Spain is now under 2%, but perinatal infections still happen, highlighting the need for ongoing efforts in prevention.
- A study involving 414 mother-child pairs found that most mothers were immigrants, predominantly contracted HIV through heterosexual transmission, and 98% received antiretroviral therapy (ART) during pregnancy.
- The study reported a very low VTR, with only 3 cases of transmission, showing that while the situation has improved significantly, early diagnosis and proper treatment are crucial for preventing infections.
Article Synopsis
- Klebsiella michiganensis is an emerging hospital pathogen that often carries antibiotic-resistance genes, including those for carbapenemases, prompting a redefined outbreak alert in a Spanish pediatric ward.
- The study analyzed 31 isolates of K. oxytoca with a focus on VIM-carbapenemase, using whole-genome sequencing to establish genetic relationships and identify resistance genes.
- The results confirmed an outbreak involving 18 cases across three wards, revealing complex interconnections and potential hidden reservoirs for the infection, underscoring the importance of genomic analysis in outbreak management.
A Local Experience of Antibiotic Lock Therapy as an Adjunctive Treatment for Central Venous Catheter-Related Bloodstream Infections in Pediatric Oncology and Hematology Patients.
Children (Basel)
August 2024
Background: One of the main drawbacks of tunneled central venous catheters (CVCs) is catheter-related bloodstream infections (CRBSIs). Antibiotic lock therapy (ALT) can be combined with systemic antibiotics to achieve catheter salvage. Our objectives are to describe cases of CRBSI and our experience with ALT in a pediatric oncology-hematology ward.
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