Publications by authors named "M L Navarrete"
Studies have shown the presence of SARS-CoV-2 in the stool of both symptomatic and asymptomatic COVID-19 patients, enabling wastewater-based surveillance (WBS) to complement clinical monitoring. The emergence of variants can enhance viral transmissibility, highlighting the need for ongoing surveillance to detect and control infectious diseases. This study aimed to detect SARS-CoV-2 variants in wastewater from a treatment plant in San Pedro de la Paz, Chile, between January and November 2021.
View Article and Find Full Text PDFAstrocytes are active cells involved in brain function through the bidirectional communication with neurons, in which astrocyte calcium plays a crucial role. Synaptically evoked calcium increases can be localized to independent subcellular domains or expand to the entire cell, i.e.
View Article and Find Full Text PDFIn recent years, peptides have gained significant relevance due to their therapeutic properties. The surge in peptide production and synthesis has generated vast amounts of data, enabling the creation of comprehensive databases and information repositories. Advances in sequencing techniques and artificial intelligence have further accelerated the design of tailor-made peptides.
View Article and Find Full Text PDFArticle Synopsis
- Tumours, especially in follicular lymphoma, show significant genetic and transcriptional diversity that influences cancer development and treatment strategies.
- The study introduces CaClust, an advanced model that combines various genomic data types to better understand tumor evolution and how genotypes translate into phenotypes.
- CaClust demonstrates improved performance over existing models and offers insights into mutations driving the disease, potential treatment targets, and confirms findings through single-cell analysis.