Publications by authors named "M L Moraga"

Article Synopsis
  • The study aims to examine how factors like physician age, sex, clinical and communication skills, and cultural background influence the prescribing of benzodiazepines (BDZ) to older adults with insomnia.
  • A cohort of international medical graduates (IMGs) treated Medicare patients from 2014-2015, and the analysis showed that U.S.-born IMGs were more likely to prescribe BDZs, particularly those from the U.K. being the least likely.
  • Findings indicate that older physicians tend to prescribe BDZs more often, suggesting that addressing these cultural and age-related factors could help reduce inappropriate medication use.
View Article and Find Full Text PDF

The South American archaeological record has ample evidence of the socio-cultural dynamism of human populations in the past. This has also been supported through the analysis of ancient genomes, by showing evidence of gene flow across the region. While the extent of these signals is yet to be tested, the growing number of ancient genomes allows for more fine-scaled hypotheses to be evaluated.

View Article and Find Full Text PDF

Background: Large-scale use of mRNA COVID-19 vaccines during the pandemic was associated with enhanced safety monitoring to ensure accurate and timely review of safety. We reviewed the mRNA-1273 (original strain) safety profile following 2 years of use (>772 million administered doses), primarily focusing on predefined safety topics (ie, adverse events of special interest [AESIs]) proposed in advance of COVID-19 vaccine use.

Methods: Cumulative mRNA-1273 safety data were included from spontaneous adverse event (AE) cases reported to Moderna's global safety database between 18 December 2020 and 17 December 2022.

View Article and Find Full Text PDF

Objectives: To analyze the mitochondrial diversity in three admixed populations and evaluate the historical migration effect of native southern population movement to Santiago (capital of Chile). The intensity of migration was quantified using three mitochondrial lineages restricted to South-Central native groups.

Methods: D-loop sequences were genotyped in 550 unrelated individuals from San Felipe-Los Andes (n = 108), Santiago (n = 217), and Concepción (n = 225).

View Article and Find Full Text PDF