Publications by authors named "M L Luppi"

This case involves a 52-year-old male, who underwent a deceased donor orthotopic liver transplant 7 months prior, presented with a 2-week history of persistent fever, anemia, thrombocytopenia, and mild elevation of liver enzymes. Upon hospital admission, the patient was febbrile, alert and oriented, hemodynamically stable. Laboratory exams revealed worsening leukopenia, anemia, thrombocytopenia, hyponatremia, and elevated ferritin.

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The recommended treatment for early glottic cancer is trans-oral laser microsurgery, with excellent oncological and functional outcomes. The aim of this study is to evaluate oncological and functional outcomes in patients who underwent monolateral type III laser cordectomy for early glottic cancer. A total of 104 patients were enrolled.

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Torpor is a state used by several mammals to survive harsh winters and avoid predation, characterized by a drastic reduction in metabolic rate followed by a decrease in body temperature, heart rate, and many physiological variables. During torpor, all organs and systems must adapt to the new low-energy expenditure conditions to preserve physiological homeostasis. These adaptations may be exploited in a translational perspective in several fields.

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Article Synopsis
  • Kaposi sarcoma herpesvirus/human herpesvirus-8 (HHV-8) poses serious health risks for solid organ transplant recipients, with higher seroprevalence noted in recipients (8.4%) compared to donors (3.3%).
  • Among transplant patients, a specific group of donors (D+) and recipients (R-) showed notable rates of HHV-8-related diseases, like Kaposi sarcoma (KS) and associated inflammatory cytokine syndrome (KICS), emphasizing the importance of careful monitoring.
  • Effective management of HHV-8 diseases, such as KICS, suggests that treatment options like rituximab can significantly impact patient outcomes, highlighting the need for serologic screening and timely interventions.
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