Publications by authors named "M L Lucchi"
We would like to express our sincere gratitude for the thoughtful reflections on our recent study regarding pulmonary metastasectomy, and we greatly appreciate the constructive dialog that our work has sparked [...
View Article and Find Full Text PDFTo investigate DNA methylation levels of a panel of genes in thymic epithelial tumors (TETs). We selected 15 genes among the most promising epigenetic biomarkers of TETs and evaluated their methylation levels in 71 TET samples. thymic carcinomas (TCs) showed hypermethylation of and genes and reduced methylation levels compared with thymomas (TMs) and healthy thymic tissues.
View Article and Find Full Text PDFArticle Synopsis
- - The Italian Lung Cancer Observational Study (LUCENT) focuses on improving understanding and treatment of non-small cell lung cancer (NSCLC) by analyzing patient outcomes in Italy, particularly for those with early and locally advanced cases.
- - The study will use a web-based registry to collect real-world data on surgical, oncological, and socioeconomic factors, aiming to inform healthcare decisions and establish national benchmarks for NSCLC treatments.
- - By evaluating both clinical and psychosocial impacts, LUCENT addresses gaps in current knowledge and aims to enhance understanding of patient experiences, with recruitment planned from January 2024 to December 2026.
Article Synopsis
- Thymomas are rare tumors that are usually treated surgically in early stages (I-II), but may require a team approach in more advanced stages (III-IV).
- This study analyzed data from 195 patients with stage II thymomas who underwent surgery between 2000 and 2020 to evaluate the effectiveness of postoperative radiotherapy (PORT) on disease-free survival (DFS).
- Results showed that PORT did not improve DFS for stage II thymomas, regardless of subtype or stage, suggesting that patients who have surgery for this condition may not benefit from additional local treatment.