Sustainable leachate treatment by integrating electrolysis with palm-shell activated carbon contactor for environmental protection.

The increasingly concerning issue of water pollution caused by untreated leachate necessitates the implementation of effective wastewater treatment methods. This study addresses the crucial issue of landfill leachate treatment through an innovative and environmentally friendly approach that integrates electrolysis with palm-shell activated carbon contactors. The efficacy of an integrated process for pollutants removal was assessed involving electrolysis with aluminum and iron electrodes, activated carbon contactors with varying bed depths, and the influence of salinity.

Anthelmintic Potential of Discarded Seeds: a sustainable approach to agricultural by-product utilization.

Objectives: (Sonn.), belonging to the Sapindaceae family, has historically been used for the treatment of gastrointestinal ailments, including ulcers, gastritis, diarrhea, and infections Plants in the Sapindaceae family have demonstrated potential anthelmintic effects, while the efficacy of remains barely investigated. seeds are often discarded as waste; however, utilizing these seeds promotes sustainable practices and may provide a natural alternative to conventional anthelmintics.

Pancreatic Safety of Tirzepatide and Its Effects on Islet Cell Function: A Systematic Review and Meta-Analysis.

Background: Endogenous glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) regulate islet cell function. GLP-1 receptor agonists (GLP-1RAs) have been associated with an elevated risk of acute pancreatitis. Data on the pancreatic safety of tirzepatide (a dual GLP-1 and GIP agonist) and its effects on islet cell function in randomized controlled trials (RCTs) are scarce.

Harnessing the TAF1 Acetyltransferase for Targeted Acetylation of the Tumor Suppressor p53.

Pharmacological reactivation of the tumor suppressor p53 remains a key challenge for the treatment of cancer. Acetylation Targeting Chimera (AceTAC), a novel technology is previously reported that hijacks lysine acetyltransferases p300/CBP to acetylate the p53Y220C mutant. However, p300/CBP are the only acetyltransferases harnessed for AceTAC development to date.

A simple analytical method for simultaneous determination of currently used pesticide (CUP) residue in river water using LC-MS/MS.

Pesticide residue monitoring in river water is obligatory for their negative ecotoxicological consequences. The current-use pesticides (CUPs) include a diverse range of synthetic pesticides registered by regulatory bodies worldwide as an alternative to the banned organochlorine pesticides (OCPs). Nowadays, CUPs are preferred for agricultural and non-agricultural purposes due to their low persistence and moderate toxicity.