Publications by authors named "M L Joffret"
Article Synopsis
- - cVDPV3s were found in wastewater samples in French Guiana between May and August 2024, indicating the detection of circulating type 3 vaccine-derived polioviruses.
- - The oral polio vaccine isn’t used in the area, suggesting these polioviruses may have been imported or derived from a vaccine strain.
- - This situation emphasizes the need for environmental monitoring to catch and eliminate any hidden poliovirus activity, which is vital for the global polio eradication effort.
Wide circulation of type 1 vaccine-derived poliovirus strains in clinical specimens from suspected cases of poliomyelitis, their contacts and in wastewater in Madagascar since late 2020.
Jonhson Raharinantoanina Marie-Line Joffret Maël Bessaud Danielle Aurore Doll Rakoto Philippe Dussart
Virology
December 2024
Madagascar has faced three major outbreaks of vaccine-derived polioviruses (VDPVs) in recent decades, with VDPV type 1 reemerging in late 2020. Here, we report the molecular characterization of these cVDPV1 strains. WHO protocols were used for poliovirus detection in stool and wastewater samples.
View Article and Find Full Text PDFArticle Synopsis
- Non-polio enteroviruses (NPEV) are viruses that can cause serious illness around the world.
- Scientists are studying blood samples to learn about how these viruses have spread in the past and what might happen in the future.
- A recent test with twelve labs showed that there are big differences in how they measure NPEV antibodies, which means we need better standard rules for testing them.
Polioviruses (PVs) are positive strand RNA viruses responsible for poliomyelitis. Many PVs have been isolated and phenotypically characterized in the 1940s-50s for the purpose of identifying attenuated strains that could be used as vaccine strains. Among these historical PVs, only few are genetically characterized.
View Article and Find Full Text PDFArticle Synopsis
- Researchers analyzed stool samples from farm animals and children in the Central African Republic (CAR) to investigate enteroviruses (EVs) and potential transmission between species.
- They found that enteroviruses in children belonged mainly to species A, B, and C, with a significant presence of EV-Cs closely related to poliovirus strains from recent vaccine-derived outbreaks.
- In animals, they identified multiple types of EV-Gs, including a new one (EV-G28), and noted evidence that some human EV-Cs could infect pigs, highlighting the risk of cross-species virus transmission in this region.