Hematopoietic stem cell transplantation (HSCT) is a potentially curative option for adults with acute lymphoblastic leukemia (ALL) who have achieved remission. This systematic review and meta-analysis compare the efficacy of total body irradiation (TBI) versus chemotherapy (CHT) based regimens for conditioning in adult ALL patients being prepared for HSCT. A comprehensive literature search was conducted in MEDLINE, Embase, the Cochrane Library, and relevant trial registries from their inception to August 2024.
View Article and Find Full Text PDFBackground: Breast cancer is a frequently diagnosed malignant disease and the primary cause of mortality among women with cancer worldwide. The therapy options are influenced by the molecular subtype due to the intricate nature of the condition, which consists of various subtypes. By focusing on the activation of receptors, Epidermal Growth Factor Receptor (EGFR) tyrosine kinase can be utilized as an effective drug target for therapeutic purposes of breast cancer.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
December 2024
Emotion recognition holds great promise in healthcare and in the development of affect-sensitive systems such as brain-computer interfaces (BCIs). However, the high cost of labeled data and significant differences in electroencephalogram (EEG) signals among individuals limit the cross-domain application of EEG-based emotion recognition models. Addressing cross-dataset scenarios poses greater challenges due to changes in subject demographics, recording devices, and stimuli presented.
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