Individual and prescription level factors associated with overdose in opioid naïve older people.

Background: Opioid naïve older adults may be at risk of overdose after receiving an initial opioid prescription.

Methods: This population-based cohort study from a linked dataset of patients in Oregon, linking all payer claims data to other administrative datasets, aimed to assess the prescription- and patient-level characteristics associated with increased odds of opioid overdose after an initial opioid prescription. Included patients were ≥65 years old and received an index pain-formulation opioid prescription between 2016 and 2019.

Navigating the definition of urban flooding: A conceptual and systematic review of the literature.

Urban flooding is a pervasive global risk, posing a great challenge to urban planners, policymakers, and particularly communities. This paper reviews the literature to analyze how urban flooding is defined across scientific disciplines. Our objectives are to uncover the elements used to define urban flooding and evaluate how these elements can impact future research and practice.

Similarity-attraction across ethnic, religious, and political groups: does celebrating differences or similarities make a difference?

Extensive research supports a positive association between similarity and attraction at the inter-personal level; the very limited research at the intergroup level is also supportive. In the context of increasing diversity in major societies, alternative diversity management approaches give priority to celebrating differences versus celebrating similarities. We tested to see if similarity-attraction at the intergroup level remains robust in conditions of celebrating differences versus similarities in four studies with ethnic (Study 1,  = 231; Study 2,  = 823), religious (Study 3,  = 1,004), and political (Study 4,  = 606) groups.

Machine Learning to Predict Interim Response in Pediatric Classical Hodgkin Lymphoma Using Affordable Blood Tests.

Purpose: Response assessment of classical Hodgkin lymphoma (cHL) with positron emission tomography-computerized tomography (PET-CT) is standard of care in well-resourced settings but unavailable in most African countries. We aimed to investigate correlations between changes in PET-CT findings at interim analysis with changes in blood test results in pediatric patients with cHL in 17 South African centers.

Methods: Changes in ferritin, lactate dehydrogenase (LDH), erythrocyte sedimentation rate (ESR), albumin, total white cell count (TWC), absolute lymphocyte count (ALC), and absolute eosinophil count were compared with PET-CT Deauville scores (DS) after two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine in 84 pediatric patients with cHL.

Nationwide Availability of and Enrollment in Medicare and Medicaid Dual-Eligible Special Needs Plans With Exclusively Aligned Enrollment.

Importance: In 2021, the Centers for Medicare & Medicaid Services designated a new category of dual-eligible special needs plans (D-SNPs) with exclusively aligned enrollment (receive Medicare and Medicaid benefits through the same plan or affiliated plans within the same organization).

Objective: To assess the availability of and enrollment in D-SNPs with exclusively aligned enrollment and to compare the characteristics of beneficiaries enrolled in D-SNPs with exclusively aligned enrollment available vs beneficiaries without such enrollment available.

Design, Setting, And Participants: Full-benefit beneficiaries enrolled in D-SNPs for 6 months or longer in 2021 or 2022.