Publications by authors named "M L Hazell"

Introduction: Introduction The Hy antigen is one of ten red cell antigens belonging to the Dombrock blood group system, with an antigen frequency of almost 100% in the majority of populations. Alloantibodies to high prevalence antigens cause difficulties with antibody identification and exclusion in serological investigations.

Case Presentation: This review describes the management of four antenatal cases where the presence of alloanti-Hy had been identified.

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One in three patients admitted to intensive care will sustain a pressure injury (PI) from a medical device. These injuries are painful and when on the face, head or neck they can result in permanent disfigurement. Preliminary evidence of the efficacy of hyper-oxygenated fatty acids (HOFAs) to prevent facial pressure injuries from medical devices is promising; however, the feasibility of incorporating HOFAs into current standard care to prevent PI from a medical device of the face, head and neck has not been extensively explored.

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Article Synopsis
  • Adalimumab is being tested as a treatment for autoimmune non-infectious uveitis (ANIU) in a trial called ASTUTE, which aims to evaluate its effectiveness and cost-effectiveness for a broader range of patients than currently approved in the UK.
  • The trial is a multicenter, placebo-controlled study, where 174 participants who respond to a 16-week run-in phase will be randomized to receive either adalimumab or placebo, focusing on treatment failure and various outcomes like visual function and quality of life.
  • Ethical approval was obtained in June 2020, and the results of the trial will be shared at international conferences and published in peer-reviewed journals to ensure widespread dissemination among professionals and patients.
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Sex- and age-based social structures have been well documented in animals with visible aggregations. However, very little is known about the social structures of snakes. This is most likely because snakes are often considered non-social animals and are particularly difficult to observe in the wild.

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