Publications by authors named "M L Hartman"
Children with cancer or hematopoietic cell transplant (HCT) frequently require ICU care. We conducted a retrospective cohort study using Healthcare Cost and Utilization Project's State Inpatient Databases from 21 U.S.
View Article and Find Full Text PDFTipping the balance of cell death: alternative splicing as a source of MCL-1S in cancer.
Cell Death Dis
December 2024
Apoptosis-regulating proteins from the B-cell lymphoma-2 (BCL-2) family are of continued interest as they represent promising targets for anti-cancer therapies. Myeloid cell leukemia-1 (MCL-1), which usually refers to the long isoform (MCL-1L) is frequently overexpressed in various types of cancer. However, MCL1 pre-mRNA can also undergo alternative splicing through exon skipping to yield the short isoform, MCL-1S.
View Article and Find Full Text PDFHealth care spending in the US reached $4.9 trillion and increased 7.5 percent in 2023, growing from a rate of 4.
View Article and Find Full Text PDFArticle Synopsis
- We study how narrow spectral holes in a doped crystal respond to temperature changes below 1 K.
- We find that around 290 mK, this response does not match traditional two-phonon Raman scattering predictions, showing a unique temperature-dependent frequency shift.
- This discovery is important for applications needing high frequency stability, like laser frequency stabilization, potentially achieving an extremely low instability of about 2×10^{-22} at 1 second.