Publications by authors named "M L Graver"

Article Synopsis
  • Acute pulmonary embolism significantly contributes to illness and mortality, and surgical pulmonary embolectomy is recommended for patients who are hypotensive.
  • A study analyzed 96 cases from 2003 to 2011 and found a 30-day mortality rate of 4.2%, with most patients recovering well.
  • Patients with severe right ventricular dysfunction who were stable had a low mortality rate of 1.4% and shorter hospital stays compared to unstable patients, suggesting the procedure can be effective but requires careful patient evaluation.
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Background: Vaginal lactobacilli protect the female genital tract by producing lactic acid, bacteriocins, hydrogen peroxide or a local immune response. In bacterial vaginosis, normal lactobacilli are replaced by an anaerobic flora and this may increase susceptibility to Neisseria gonorrhoeae, a facultative anaerobe. Bacterial interference between vaginal lactobacilli and N.

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Neisseria gonorrhoeae will grow in an anaerobic atmosphere if provided with nitrite as a terminal electron acceptor, and it is increasingly apparent that this important pathogen may grow anaerobically in vivo. By modifying a previously described chemically-defined medium we have produced a liquid medium capable of supporting growth of N. gonorrhoeae under strictly anaerobic conditions.

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Hepatocyte transplantation is being used in patients with liver-based metabolic disorders and acute liver failure. Hepatocytes are isolated from unused donor liver tissue under GMP conditions. Cells must be free of microbiological contamination to be safe for human use.

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