Publications by authors named "M L Gonzalez-Casaus"
Article Synopsis
- The study investigates the connection between inflammatory biomarkers and cardiovascular events in type 2 diabetes patients with stable coronary artery disease (CAD).
- A total of 964 patients were analyzed, measuring inflammatory markers such as TNF-R1, GDF-15, and hsCRP, to see how these relate to acute ischemic events over a follow-up period of about 5.4 years.
- Results showed that diabetic patients had higher inflammatory marker levels and a greater incidence of cardiovascular events, with TNF-R1 identified as an independent risk factor for these events specifically in diabetic patients.
Sarcopenia and dynapenia are two terms associated with ageing that respectively define the loss of muscle mass and strength. In 2018, the European Working Group on Sarcopenia in Older People (EWGSOP) introduced the EWGSOP2 diagnostic algorithm for sarcopenia, which integrates both concepts. It consists of 4 sequential steps: screening for sarcopenia, examination of muscle strength, assessment of muscle mass and physical performance; depending on these last 3 aspects sarcopenia is categorised as probable, confirmed, and severe respectively.
View Article and Find Full Text PDFBone is more than a reservoir of calcium and phosphorus. Its lacuno-canalicular arrangement provides an important pathway for exchange with circulation and currently, the skeleton is considered a large endocrine organ with actions that go beyond the control of calcium-phosphorus balance mediated by fibroblastic growth factor 23 (FGF23). Parallel to the modulating effect of adipokines on bone turnover, certain bone proteins, such as osteocalcin and sclerostin, play a counter-regulatory role on energy metabolism, probably in an attempt to ensure its high energy requirement for bone turnover.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates the relationship between mineral metabolism (MM) and cardiac rehabilitation (CR) in patients who experienced acute coronary syndrome (ACS).
- A total of 58 patients undergoing CR were compared with 116 control patients, revealing significant differences in hypertension prevalence and medication use.
- Results showed that after six months, klotho levels increased significantly in CR patients, while controls experienced a decrease, suggesting a potential positive effect of CR on MM that warrants further exploration.