Publications by authors named "M L Efthymiou"
Article Synopsis
- - This study examined the occurrence and effects of antinuclear antibodies (ANA) in patients with antiphospholipid antibodies (aPL) but without other systemic autoimmune diseases, using data from the APS ACTION Registry.
- - Among the 430 analyzed patients, 56% tested positive for ANA, revealing significant links between ANA positivity and various autoimmune features like hematologic issues and joint involvement.
- - Despite the presence of these autoimmune characteristics in ANA-positive patients, the study found no connection between ANA status and complications related to thrombosis or pregnancy; interestingly, ANA-negative patients had more pregnancies and live births.
Article Synopsis
- Strictures following liver transplantation are a common complication, and while endoscopic retrograde cholangiopancreatography (ERCP) is typically the first line of treatment, it can fail, necessitating further procedures.
- This study reviewed the use of a digital single operator cholangioscope (D-SOC) at two Australian centers to assist patients who had unsuccessful ERCP attempts for biliary strictures.
- Out of 18 patients treated with D-SOC, 72% successfully achieved guidewire access, with some patients avoiding more invasive procedures, indicating D-SOC's potential as a viable option before resorting to less favorable techniques like percutaneous transhepatic cholangiography (PTC) or surgery.
Background And Aim: Data on post-endoscopic retrograde cholangiopancreatography (ERCP) adverse events and readmission rates in liver transplantation (LT) patients remain scarce. This study determined the 30-day procedure-related readmission rate following ERCP in an LT cohort at an Australian tertiary academic center.
Methods: All unplanned readmissions within 30 days following ERCP in orthotopic LT patients between December 2012 and August 2021 were retrospectively identified.
Background: Optimal secondary prevention antithrombotic therapy for patients with antiphospholipid syndrome (APS)-associated ischemic stroke, transient ischemic attack, or other ischemic brain injury is undefined. The standard of care, warfarin or other vitamin K antagonists at standard or high intensity (international normalized ratio (INR) target range 2.0-3.
View Article and Find Full Text PDFComparison of clinical and serological features in thrombotic antiphospholipid syndrome patients, with and without associated systemic lupus erythematosus, followed for up to 42 years: A single centre retrospective study.
Lupus
September 2024
Objective: To assess the impact of concomitant systemic lupus erythematosus (SLE) on the clinicopathological manifestations of thrombotic antiphospholipid syndrome (APS).
Methods: This single-centre, retrospective study compared clinical and antiphospholipid antibody (aPL) data from 118 patients, 58 with SLE-associated APS (SLE-APS), and 60 with primary APS.
Results: Median follow-up was 13.