"Cracking" the Code on Nitrous Oxide Safety in the Dental Setting.

Nitrous oxide-oxygen sedation is typically regarded as the safest in-office inhalational sedation method dentists can employ when treating patients with dental fear and/or anxiety. Despite a considerable inherent margin of safety with nitrous oxide-oxygen administration as a means to provide analgesia and anxiolysis in the dental office, concerns among staff workers about potential harm from environmental exposure over time have led to efforts to mitigate occupational exposure. Concerns over nitrous oxide's high global warming potential have also emerged.

Functional Roles and Host Interactions of Non-Structural Proteins During Replication.

, a genus encompassing arthropod-borne, positive-sense, single-stranded RNA viruses in the family, represents clinically relevant viruses that pose significant threats to human and animal health worldwide. With warming climates and persistent urbanization, arthropod vectors and the viruses they transmit continue to widen their geographic distribution, expanding endemic zones. Flaviviruses such as dengue virus, Zika virus, West Nile virus, and tick-borne encephalitis virus cause debilitating and fatal infections globally.

An event-related potential study of onset primacy in visual change detection.

Onset primacy is a behavioural phenomenon whereby humans identify the appearance of an object (onset) with greater efficiency than other kinds of visual change, such as the disappearance of an object (offset). The default mode hypothesis explains this phenomenon by postulating that the attentional system is optimised for onset detection in its initial state. The present study extended this hypothesis by combining a change-detection task and measurement of the P300 event-related potential, which was thought to index the amount of processing resources available to detecting onsets and offsets.