Simple oral mucosal epithelial transplantation (SOMET) for ocular surface reconstruction in Stevens-Johnson Syndrome: A case report.

Introduction: We report the clinical outcome of a novel surgical technique called simple oral mucosal epithelial transplantation (SOMET) for the treatment of limbal stem cell deficiency (LSCD) in a patient with Stevens-Johnson Syndrome (SJS).

Presentation Of Case: An eighteen-year-old girl was diagnosed as having chronic bilateral ocular sequelae of SJS. She initially underwent mucous membrane grafting (MMG) in both eyes for lid margin keratinization.

Aqueous-deficient dry eye disease: Preferred practice pattern guidelines on clinical approach, diagnosis, and management.

Dry eye disease (DED) is a broad term that includes a diverse group of clinical disorders. Aqueous-deficient dry eye (ADDE), a subtype of DED, is characterized by decreased tear production by the lacrimal gland. It can be seen in up to one-third of individuals with DED and can be comorbid with a systemic autoimmune process or occur secondary to an environmental insult.

Effect of substituents in chlorin e derivatives on the loading efficiency of the photosensitizer into the liposome membrane and their biological activity.

In this work, we incorporated the hydrophobic alkylamide and hydroxyalkylamide derivatives of chlorin e into the lipid bilayer of liposomes. We obtained the data on the effectiveness of incorporation of studied compounds and have determined the size of liposomes and their stability when stored in liquid form. We also investigated the bioactivity of chlorin photosensitizers and compared the photodynamic activity of studied compounds in free and liposomal forms.

Management of an unresponsive case of HSV keratouveitis with trabeculectomy and DSAEK: A case report.

Introduction And Importance: This case demonstrates an unusual presentation of Herpes simplex virus (HSV) ocular infection and the challenges faced during the management of its complications.

Presentation Of The Case: A thirty year-old lady, a steroid responder with HSV keratouveitis, was referred for non-response to treatment with the prophylactic dose of oral acyclovir and acetazolamide. She presented with large epithelial bullae, anterior chamber reaction, and raised intraocular pressure in her right eye.

Clinical and Microbiological Spectra and Therapeutic Outcomes of Polymicrobial Keratitis.

Purpose: The aim of this study was to evaluate the risk factors, microbiology, and treatment outcomes of polymicrobial keratitis (PMK).

Methods: We retrospectively analyzed 65 patients diagnosed with PMK between 2016 and 2019. The clinical and microbiological characteristics and outcomes were evaluated.