Prologue for a synoptic catalog: combining a hospital library catalog and a bookseller's catalog.

This article introduces the synoptic catalog, a computerized combination of a hospital library catalog and a bookseller's catalog. Majors Scientific Books and Richmond Memorial Hospital Libraries in Virginia collaborated to develop the model. A logical evolution in catalog theory and practice, the design expands the identification, collocation, and evaluation functions of the traditional library catalog.

Glucose metabolism of Haemonchus contortus adults: effects of thiabendazole on susceptible versus resistant strain.

Analyses of the in vitro glucose metabolism of Haemonchus contortus adults have confirmed a complex series of end-products: ethanol, n-propanol, propionate, acetate, and CO2 as the major end-products of catabolism. No difference in end-product accumulation was seen between the cambendazole sensitive (BPL) and cambendazole resistant (CR) strains. Thiabendazole (5 mM) in vitro depressed ethanol, propanol, acetate, and propionate accumulation by approximately 42% in the BPL strain.

Inheritance of cambendazole resistance in Haemonchus contortus.

Fourth-molt larvae (M4) of cambendazole-resistant (CBZ-R) and cambendazole-susceptible (BPL) strains of Haemonchus contortus were recovered from donor lambs and inoculated orally into source lambs to effect mating in 2nd lamb. Eggs produced by these parasitic matings were collected, cultured, and inoculated into lambs to compare the anthelmintic activity of cambendazole (CBZ), given at a dose rate of 20 mg/kg, against the F1 adults with its activity against the 2 parenteral strains (CBZ-R and PBL). In 2 replications, CBZ was 94% and 99% efficacious against the progeny of the cross matings and 91% and 95% against the BPL strain; CBZ was only 39% and 42% efficacious against the CBZ-R strain.