Publications by authors named "M L Churchill"
Article Synopsis
- The study aims to assess the impacts of early screening for palliative care in ICU patients to align their care with personal goals and potentially shorten their ICU stays.* -
- Using a retrospective cohort approach, researchers compared ICU admissions before and after implementing palliative care screening, focusing on how this screening affected the use of specialist palliative care and various patient outcomes.* -
- Results showed that after screening implementation, there was a significant increase in early palliative care consultations (17% vs 1%), indicating a positive shift in palliative care use following the new protocol.*
Article Synopsis
- Childhood sleep quality is influenced by factors such as maternal stress during pregnancy and can predict later health outcomes.
- The study examined data to understand how prenatal stress relates to sleep quality in children aged 4-8, finding that both prenatal and postnatal stress have significant effects.
- Results indicate that postnatal stress mediates the impact of prenatal stress on sleep issues, highlighting the need for further research on maternal mental health and child sleep disturbances.
Objective: The aim of this study was to evaluate the efficacy and safety of intravenous (IV) secukinumab in patients with active psoriatic arthritis (PsA).
Methods: INVIGORATE-2 (NCT04209205) was a randomized, placebo-controlled, phase 3 trial. Patients with active PsA were randomized 1:1 to receive IV secukinumab (6 mg/kg at baseline followed by 3 mg/kg every four weeks [q4w]) or placebo.
HIV persistence in the brain is a barrier to cure, and potentially contributes to HIV-associated neurocognitive disorders. Whether HIV transcription persists in the brain despite viral suppression with antiretroviral therapy (ART) and is subject to the same blocks to transcription seen in other tissues and blood, is unclear. Here, we quantified the level of HIV transcripts in frontal cortex tissue from virally suppressed or non-virally suppressed people with HIV (PWH).
View Article and Find Full Text PDFBackground: Despite surgical and pharmacological interventions, endometriosis can recur. Reliable information regarding risk of recurrence following a first diagnosis is scant. The aim of this study was to examine clinical and survey data in the setting of disease recurrence to identify predictors of risk of endometriosis recurrence.
View Article and Find Full Text PDF