Publications by authors named "M L Chiozza"
Article Synopsis
- - The study discusses advancements in laparoscopic right hemicolectomy, emphasizing the importance of complete mesocolic excision (CME) and central vascular ligation (CVL) for colon cancer surgery, particularly based on findings from the CoDIG 1 and CoDIG 2 studies in Italy.
- - Researchers aimed to use machine learning techniques (MLTs) to accurately predict the postoperative length of stay (LoS) for patients undergoing this procedure, training algorithms like random forest (RF) and support vector machine (SVM) on large patient datasets.
- - Results showed that the RF algorithm achieved high accuracy in predicting longer stays, with key predictors identified, such as fast-track protocols and drainage, indicating that MLTs could
Colorectal cancer, the third most common cancer worldwide, affects 40-45% of patients on the right side. Surgery, especially minimally invasive methods such as laparoscopic and robotic procedures, is the preferred treatment. However, these techniques present technical complications.
View Article and Find Full Text PDFBackground: Colon cancer is a disease with a worldwide spread. Surgery is the best option for the treatment of advanced colon cancer, but some aspects are still debated, such as the extent of lymphadenectomy. In Japanese guidelines, the gold standard was D3 dissection to remove the central lymph nodes (203, 213, and 223), but in 2009, Hoenberger et al.
View Article and Find Full Text PDFA Randomized Phase III Trial of Complete Mesocolic Excision Compared with Conventional Surgery for Right Colon Cancer: Interim Analysis of a Nationwide Multicenter Study of the Italian Society of Surgical Oncology Colorectal Cancer Network (CoME-in trial).
Ann Surg Oncol
March 2024
Background: Although complete mesocolic excision (CME) is supposed to be associated with a higher lymph node (LN) yield, decreased local recurrence, and survival improvement, its implementation currently is debated because the evidence level of these data is rather low and still not supported by randomized controlled trials.
Method: This is a multicenter, randomized, superiority trial (NCT04871399). The 3-year disease-free survival (DFS) was the primary end point of the study.
: In Italy, on December 2020, workers in the education sector were identified as a priority population to be vaccinated against COVID-19. The first authorised vaccines were the Pfizer-BioNTech mRNA (BNT162b2) and the Oxford-AstraZeneca adenovirus vectored (ChAdOx1 nCoV-19) vaccines. : To investigate the adverse effects of two SARS-CoV-2 vaccines in a real-life preventive setting at the University of Padova.
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