Publications by authors named "M L Caspani"

Purpose: The lateral Trendelenburg position (LTP) may hinder the primary pathophysiologic mechanism of ventilator-associated pneumonia (VAP). We investigated whether placing patients in the LTP would reduce the incidence of VAP in comparison with the semirecumbent position (SRP).

Methods: This was a randomized, multicenter, controlled study in invasively ventilated critically ill patients.

View Article and Find Full Text PDF

Objective: To evaluate cross-sectional patient distribution and standardised 30-day mortality in the intensive care units (ICU) of an inclusive hub and spoke trauma system.

Setting: ICUs of the Integrated System for Trauma Patient Care (SIAT) of Emilia-Romagna, an Italian region with a population of approximately 4.5 million.

View Article and Find Full Text PDF
Article Synopsis
  • Intracranial pressure (ICP) monitoring is crucial for managing traumatic brain injury (TBI) following primary decompressive craniectomy (DC) after emergency hematoma evacuation, a topic with limited existing research.
  • A study analyzed data from 34 patients and found a significant incidence of intracranial hypertension and low cerebral perfusion pressure (CPP), which were linked to worse neurological outcomes as measured by the Glasgow Outcome Scale (GOS).
  • ICP monitoring effectively guided treatment strategies for managing complications like intracranial hypertension, with therapies applied including barbiturate coma, external ventricular drainage, and removal of hematomas.
View Article and Find Full Text PDF

Objective: To evaluate the cerebral and hemodynamic effects of low-dose intramuscular diclofenac sodium (DCFS) administered for fever control in patients with acute brain injury in the intensive care unit.

Methods: Inclusion criteria for this prospective clinical study were age ≥18 years; the ability to monitor intra-arterial blood pressure, core body temperature, and intracranial pressure; the placement of an indwelling jugular venous catheter for intermittent jugular venous oxygen saturation measurements; and a core body temperature ≥37.5°C.

View Article and Find Full Text PDF

Background: The aim of this study was to evaluate the association between fever after the first days of ICU stay and neurological outcome after cardiac arrest (CA).

Methods: We retrospectively analyzed CA patients admitted to intensive care unit (ICU).

Inclusion Criteria: age ≥18 years, Glasgow Coma Scale score ≤8 at ICU admission and assessment of body core temperature (BCT) using bladder or intravascular probes.

View Article and Find Full Text PDF