Publications by authors named "M L Casas"
Channels, Transporters, and Receptors at Membrane Contact Sites.
Contact (Thousand Oaks)
December 2024
Membrane contact sites (MCSs) are specialized regions where two or more organelle membranes come into close apposition, typically separated by only 10-30 nm, while remaining distinct and unfused. These sites play crucial roles in cellular homeostasis, signaling, and metabolism. This review focuses on ion channels, transporters, and receptors localized to MCSs, with particular emphasis on those associated with the plasma membrane and endoplasmic reticulum (ER).
View Article and Find Full Text PDFObjectives: The present study performed a systematic review of the scientific literature that deals with the academic performance of university students with ADHD, collecting the research conducted between 2018 and 2024. Likewise, we aimed to know the factors that influence on academic performance and evaluate the tools used in the collection of ADHD symptoms and educational data.
Methods: The electronic databases PubMed, PsycInfo, and Scopus were used to search studies using PRISMA guidelines.
Article Synopsis
- - Gliomatosis cerebri (GC) is a rare brain cancer that presents with vague symptoms, often including parkinsonism and neurocognitive issues, making it hard to diagnose.
- - A 78-year-old patient with no significant medical history experienced worsening balance, tremors, and cognitive decline, leading to an MRI that indicated abnormal white matter changes.
- - A biopsy confirmed the diagnosis of GC as diffuse astrocytoma, emphasizing that MRI is crucial for diagnosis, but a biopsy is necessary for confirmation due to the nonspecific nature of symptoms.
Background: Vitamin C plays key roles in cellular homeostasis, functioning as a potent antioxidant and a positive regulator of cell differentiation. In skeletal muscle, the vitamin C/sodium co-transporter SVCT2 is preferentially expressed in oxidative slow fibers. SVCT2 is up-regulated during the early fusion of primary myoblasts and decreases during initial myotube growth, indicating the relevance of vitamin C uptake via SVCT2 for early skeletal muscle differentiation and fiber-type definition.
View Article and Find Full Text PDFBackground: The effectiveness of colonoscopy in preventing colorectal cancer (CRC) within opportunistic screening programs has not been clearly established. The aim of this study was to analyze the effectiveness of colonoscopy within an opportunistic screening program using nested case-control study.
Methods: Subjects who received a diagnosis of CRC (CG) between the ages of 50 and 90 years were included and matched by age and gender in a 1:5 ratio with patients without CRC diagnosis (COG) during the period 2015 to 2023.