Bright and long-lasting aqueous peroxyoxalate chemiluminescence in cellulose microspheres.

Water decreases the brightness of the peroxyoxalate chemiluminescence partially due to the hydrolysis of the oxalate reagent. Here, we show that encapsulation of an oxalate ester and the fluorescent activator in microspheres of cellulose esters increases the emission intensity 30 times compared to the same reaction in water without encapsulation, whereas the emission intensity decay rate constants are considerably lower. Emission intensities, rate constants and chemiluminescence quantum yields increase with increasing hydrogen peroxide concentrations.

Development of Fluorine-Free Electrolytes for Aqueous-Processed Olivine-Type Phosphate Cathodes.

Environmental impacts and resource availability are significant concerns for the future of lithium-ion batteries. This study focuses on developing novel fluorine-free electrolytes compatible with aqueous-processed cobalt-free cathode materials. The new electrolyte contains lithium 1,1,2,3,3-pentacyanopropenide (LiPCP) salt.

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes.

Reactive oxygen and nitrogen species are small reactive molecules derived from elements in the air─oxygen and nitrogen. They are produced in biological systems to mediate fundamental aspects of cellular signaling but must be very tightly balanced to prevent indiscriminate damage to biological molecules. Small molecule probes can transmute the specific nature of each reactive oxygen and nitrogen species into an observable luminescent signal (or even an acoustic wave) to offer sensitive and selective imaging in living cells and whole animals.

Occurrence of multi-carbapenemase-producing Enterobacterales in a tertiary hospital in Madrid (Spain): A new epidemiologic scenario.

Introduction: Multi-carbapenemase-producing Enterobacterales (M-CPE) are increasingly described. We characterized the M-CPE isolates prospectively recovered in our hospital (Madrid, Spain) over two years (2021-2022).

Methods: We collected 796 carbapenem resistant Enterobacterales (CRE) from clinical and surveillance samples.

Beyond lectures and practical courses: Teaching pharmacology using imaginative pedagogical tools.

Pharmacology has broadened its scope considerably in recent decades. Initially, it was of interest to chemists, doctors and pharmacists. In recent years, however, it has been incorporated into the teaching of biologists, molecular biologists, biotechnologists, chemical engineers and many health professionals, among others.