Publications by authors named "M L Brake"

The Dromedary camel has a remarkable history amongst cultures across Asia and northern Africa, serving multiple purposes ranging from providing milk, textiles, racing, and acting as pack animals. Recent genetic studies have revealed that many dromedaries are genetically homogenous, indicating that they do not represent different breeds, advocating for camel 'type' over camel 'breed'. In this study, we leveraged whole genome sequencing (WGS) to sequence 15 Jordanian Alia camels for the first time, alongside 9 Jordanian mixed camels from diverse locations within the country.

View Article and Find Full Text PDF

Three-dimensional (3D)-printed custom pelvic implants have become a clinically viable option for patients undergoing pelvic cancer surgery with resection of the hip joint. However, increased clinical utilization has also necessitated improved implant durability, especially with regard to the compression screws used to secure the implant to remaining pelvic bone. This study evaluated six different finite element (FE) screw modeling methods for predicting compression screw pullout and fatigue failure in a custom pelvic implant secured to bone using nine compression screws.

View Article and Find Full Text PDF

Type of feed is an important consideration in herbivore colony management, yet limited studies report on the effects of diet on common conditions such as urolithiasis in guinea pigs. Urolithiasis is a well-documented cause of lower urinary tract disease in guinea pigs, with calcium carbonate uroliths reported as the predominant calculi formed in the guinea pig urinary tract. A calcium-rich diet has been suggested as a risk factor for of urolithiasis, with numerous commercially available guinea pig diets formulated for adults avoiding ingredients that are higher in calcium.

View Article and Find Full Text PDF

The complete mitochondrial genome of the olive cultivar Mehras was determined using high-throughput sequencing technology. It consisted of 710,808 base pairs and comprised 70 genes, including 44 protein-coding genes, 23 tRNA genes, and three rRNA genes, with a GC content of 44.7%.

View Article and Find Full Text PDF
Article Synopsis
  • Mice are commonly used in influenza research because they are easy to handle and show clear signs of infection, but analgesia is often avoided in studies due to potential impact on the results.
  • There is a concern that using pain relief medications could confound primary study outcomes like infection progression and immune response.
  • This study found that administering extended-release buprenorphine for pain relief in mice did not affect their clinical signs, mortality, or antibody responses, suggesting it can be safely used for animal welfare without impacting research results.
View Article and Find Full Text PDF