The duration of incoherent XUV pulses down to the femtoseconds (fs) can be retrieved through a statistical analysis of the modulations on the observed radiation spectrum. Uncorrelated shot-noise fluctuations in the pulse temporal profile result in incoherent radiation showing a multispike spectrum where the spike width is inversely proportional to the pulse length. In this Letter, single-shot temporal characterization of the betatron radiation pulses emitted by fs-long, 100's MeV electron bunches undergoing acceleration, and propagating through a plasma wiggler was performed in the XUV domain.
View Article and Find Full Text PDFRestrictive diets for the treatment of different gastrointestinal disorders are reported to change the composition of intestinal microbiota. Recently, it has been proposed that individuals with histamine intolerance suffer from intestinal dysbiosis, having an overabundance of histamine-secreting bacteria, but how it is still unknown this state is affected by the usual dietary treatment of histamine intolerance [i.e.
View Article and Find Full Text PDFHypersaline endorheic aquatic systems (H-SEAS) are lakes/shallow playas in arid and semiarid regions that undergo extreme oscillations in salinity and severe drought episodes. Although their geochemical uniqueness and microbiome have been deeply studied, very little is known about the availability and quality of dissolved organic matter (DOM) in the water column..
View Article and Find Full Text PDFAn underlying cause of histamine intolerance is diamine oxidase (DAO) deficiency, which leads to defective homeostasis and a higher systemic absorption of histamine. Impaired DAO activity may have a genetic, pharmacological or pathological origin. A recent proposal also suggests it can arise from an alteration in the gut microbiota, although only one study has explored this hypothesis to date.
View Article and Find Full Text PDFNew drugs that target species, the causative agents of malaria, are needed. The enzyme -myristoyltransferase (NMT) is an essential protein, which catalyzes the myristoylation of protein substrates, often to mediate membrane targeting. We screened ∼1.
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