Publications by authors named "M L A Morssinkhof"

Chronotype, an individual's preferred sleep-wake timing, is influenced by sex and age. Men sometimes report a later chronotype than women and older age is associated with earlier chronotype. The sex-related changes in chronotype coincide with puberty and menopause.

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Article Synopsis
  • - Women generally experience higher rates of depression and differing symptoms than men, potentially due to sex hormones, which is also relevant for transgender individuals using Gender-Affirming Hormone Therapy (GAHT) who face elevated depression risks.
  • - A study with 110 transmasculine (TM) and 89 transfeminine (TF) participants analyzed depressive symptoms before and after 3- and 12-months of GAHT, identifying four symptom clusters: mood, anxiety, lethargy, and somatic symptoms; findings indicated TM showed improvements in lethargy while TF reported a slight increase in low mood.
  • - Limitations of the study include a small follow-up sample size after 12 months and the absence of important
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Study Objectives: Sex differences in sleep architecture are well-documented, with females experiencing longer total sleep time, more slow wave sleep (SWS), and shorter Rapid Eye Movement (REM) sleep duration than males. Although studies imply that sex hormones could affect sleep, research on exogenous sex hormones on sleep architecture is still inconclusive. This study examined sleep architecture changes in transgender individuals after 3 months of gender-affirming hormone therapy (GAHT).

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Study Objectives: Transgender persons can use gender-affirming hormone therapy (GAHT) to align their physical appearance with their identified gender. Many transgender persons report poor sleep, but the effects of GAHT on sleep are unknown. This study examined the effects of a 12 months of GAHT use on self-reported sleep quality and insomnia severity.

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  • Oral contraceptives (OCs) are widely used for birth control but may be linked to increased symptoms of depression and insomnia, especially in women with a history of depression.
  • This study aimed to explore the relationship between OC use and symptoms of major depressive disorder (MDD), dysthymia, and insomnia among adult women, examining whether prior depression influences these symptoms during OC use.
  • Results from a sample of over 2,000 measurements indicated that OC use did not significantly correlate with heightened severity of depressive or insomnia symptoms when compared to women who cycle naturally without OCs.
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