Publications by authors named "M Kuricova"
Obesity is considered an important factor contributing to the development of atherosclerosis. Inflammation plays a key role in endothelial dysfunction (ED), an initial stage of the atherosclerotic process. Several microRNAs (miRNAs) may play an important role in the inflammatory process, but there is a lack of information about their participation in the early stages of atherosclerosis development in patients with obesity.
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- * A total of 62 healthy dogs and 13 CKD-affected dogs were analyzed, with findings showing no sex differences; however, age was a factor, with older dogs (>6 years) having higher NAG/creatinine (Cr) ratios compared to younger ones (2-6 years).
- * The lowest NAG/Cr ratio was found in dogs with CKD stage 2, and while the study established a reference range for NAG/Cr, no significant correlations
The aim of this study was to determine the reference values of cartilage damage biomarkers in the blood and urine in 76 clinically healthy German Shepherd dogs. We grouped the dogs into 4 groups by age. All the groups were consistently made up of 19 dogs.
View Article and Find Full Text PDFNon-surgical pain management for hip joint disease in veterinary medicine.
Vet Med (Praha)
August 2024
Article Synopsis
- Hip dysplasia is a common problem in dogs where their hip joint doesn't fit together properly, causing pain and stiffness.
- Currently, surgery is the main way to fix it, but other treatments focus on reducing pain and strengthening muscles using methods like hydrotherapy.
- New research is looking at special cells called mesenchymal stem cells (MSCs) and treatments like platelet-rich plasma (PRP) to help heal the cartilage in dogs with osteoarthritis.
Article Synopsis
- * Results showed that urinary uromodulin levels correlated with kidney disease markers in stage 1 CKD and were significantly lower in dogs at stage 2, particularly in Belgian shepherds compared to German shepherds.
- * The research suggests that urinary uromodulin may be a better indicator of CKD than serum uromodulin, but further studies with more subjects are needed to confirm its effectiveness as an early-stage disease marker.