Screening for congenital hypothyroidism: the value of retesting after four weeks in neonates with low and very low birth weight.

Objectives: Thyroid-stimulating hormone (TSH), normally a reliable screening test for congenital hypothyroidism (CH), may fail to detect cases among infants who have low and very low birth weight. The purpose of this study was to identify neonates with false-negative screening results.

Setting: A province in Poland in which 3,854 neonates had body weight View Article and Find Full Text PDF

[Incidence of Graves disease in children in some regions of south-eastern Poland].

The aim of the studies was the assessment of Graves disease (G-D) incidence in children aged 0-15 years who inhabited the Krakowskie (K), Nowosadeckie (N) and Rzeszowskie (Rz) provinces in the years 1989-1996. The incidence of G-D was evaluated depending on the age, sex and place of residence (urban vs. rural area).

Iodine deficiency disorders incidence in neonates based on the experience with mass screening for congenital hypothyroidism in southeast Poland in the years 1985-2000.

Thyroid hormones are very important for the child mental and physical development. In southeast Poland screening for congenital hypothyroidism detection was established in 1985; this region was defined as an iodine deficient area. The results provided the first signal pointing to insufficient iodine prophylaxis in the region.

[TSH levels in newborn with low and very low birth weight vs rescreening for congenital hypothyroidism].

Unlabelled: A disorder of thyroid function, as stated by various references, is very common among children with low and very low body weight. Also, the concentration of thyroid hormones in this group differs from that of neonates full term with the adequate body weight. In 1998, in southeastern Poland, a repeated screening for TSH level in blood spots on filter paper was introduced among neonates with low and very low birth-weight.

Natural history of asplenism in APECED--patient report.

Only a few reports on patients with hypo/ asplenism associated with APECED have been published, yet hyposplenism has been found in approximately half of the studied patients. The 7-year follow-up in our only patient with APECED revealed a decrease of spleen size from normal to half-size by ultrasound and CT examinations. Scintigraphy of the liver and spleen demonstrated a progressively diminishing splenic uptake of the tracer from low to complete absence.