Publications by authors named "M Kumihashi"
Purpose: We have investigated the absorption dynamics of petroleum fuel components from the analytical results of autopsy samples.
Methods: Post-mortem samples of the severely burned case, including femoral blood, intratracheal contents (mucus) and intratracheal gas-phase samples were collected, and analysed by gas chromatography-mass spectrometer with head-space solid-phase microextraction.
Results: The composition of flammable substances in the tracheal gas phase differed slightly from that in mucus.
Article Synopsis
- - A man in his forties was found dead at a friend's house, with toxicological analysis revealing fatal levels of caffeine and other drugs commonly found in an over-the-counter cough medicine called BRON, which is sold in Japan.
- - The analysis showed significant concentrations of caffeine, chlorpheniramine, dihydrocodeine, and methylephedrine, with caffeine being classified as a methylxanthine and primarily metabolized by cytochrome P450 (CYP)1A2, which can be inhibited by fluvoxamine.
- - The study concluded that his death resulted from an overdose of BRON, highlighting the need to consider drug interactions, as fluvoxamine's inhibition of caffeine metabolism likely increased his caffeine
A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of pentobarbital, phenobarbital, duloxetine, acetaminophen and tramadol were 10.39, 22.
View Article and Find Full Text PDFWe present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.
View Article and Find Full Text PDFThe findings of histological examination and the results of energy-dispersive X-ray spectrometry (EDX) analysis were compared to identify skin metallization in experimental electrical injury. Rats were divided into three experimental groups (n = 5, each group): control, current exposure for five seconds, and current exposure for ten seconds. A relatively high peak of copper, which was used as an electrical conductor, was detected in formalin-fixed skin samples of the two current exposure groups by EDX.
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