Publications by authors named "M Kuligowski"
Increasing the consumption of fruit and vegetables can be achieved by creating new products. A promising method seems to be the directed fermentation of vegetables. The aim of this study was to investigate the effect of ultrasonic pretreatment (US; 25 kHz; 5 min) and the lactic acid bacteria strain (LAB; 299v and GG) on the quality of fermented pumpkin ( L.
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- Atopic dermatitis (AD) affects around 7% of adolescents worldwide, and a new topical cream containing ruxolitinib (a JAK 1/JAK2 inhibitor) showed promise in treating this condition in two phase 3 trials.
- The study focused on patients aged 12-17 and assessed the safety and effectiveness of 1.5% ruxolitinib cream compared to a placebo, with evaluations at the 8-week mark and during a long-term safety period of up to 52 weeks.
- Results indicated that a significant portion of participants using the 1.5% cream experienced substantial improvements in skin condition and itchiness, with 89% choosing to continue the treatment in the long-term
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- Menopause leads to hormonal changes that negatively affect bone health, increasing the risk of fractures, prompting research on the effects of daidzein and tempeh on calcium and bone metabolism in ovariectomized rats.
- In a two-phase experiment with 40 female Wistar rats, dietary interventions were tested in five groups, revealing that the tempeh group significantly increased bone turnover markers compared to others.
- Histological results showed that both daidzein and tempeh functions similarly to bisphosphonates, suggesting that these isoflavones may enhance calcium status and bone metabolism, possibly due to their estrogen-like properties.
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- Isoflavones and probiotics, along with magnesium, are believed to support bone health, and this study focused on their effects on the magnesium status of healthy female rats.
- Forty-eight rats were divided into six groups, where some received a standard diet and others had additional ingredients like tempeh flour and pure daidzein or genistein.
- Results showed that while tempeh influenced magnesium levels in various tissues, there was no significant effect from pure daidzein or genistein, although consuming tempeh might enhance magnesium status overall.
Article Synopsis
- - The study focuses on the role of calcium in bone health and examines how isoflavones (like daidzein and genistein) and probiotics affect calcium transporters in healthy female rats, aiming to understand their impact on bone metabolism and serum calcium levels.
- - Results indicated that a diet rich in daidzein and genistein significantly increased gene expression of the Trpv6 calcium transporter in the duodenum and lowered serum levels of pyridinoline, a bone metabolism biomarker, but no major effects were seen with tempeh and soybean diets.
- - Overall, the findings suggest that while isoflavones may enhance calcium transport and reduce certain bone biomarkers, the combination of these dietary components did not result