Publications by authors named "M Kuehnert"
Article Synopsis
- - A survey of US infectious disease specialists found that 61 reported cases of Bartonella quintana infections from 2014 to 2024.
- - Key challenges in diagnosing these infections are a lack of awareness among healthcare providers, insufficient testing, and uneven access to healthcare for affected groups.
- - To enhance patient outcomes, it's crucial to improve early recognition of B. quintana infections.
Article Synopsis
- - Bartonella quintana can lead to serious health issues, including endocarditis and chronic infections, and is mainly spread by body lice, particularly in homeless populations.
- - A case study in the U.S. highlighted two kidney transplant recipients who contracted the infection from an organ donor who was homeless; one case was atypical while the other showed mild symptoms.
- - Timely detection and treatment allowed both recipients to recover, emphasizing the importance of assessing organ donors' living conditions, specifically those with a history of homelessness or lice infestations, for potential B. quintana infections in transplant recipients.
Article Synopsis
- Bartonella quintana infection can cause serious health issues like bacillary angiomatosis and culture-negative endocarditis, mainly affecting individuals who are homeless.
- In a study conducted in New York City between January 2020 and November 2023, five cases of left-sided, culture-negative endocarditis were identified in unsheltered homeless persons using molecular methods.
- Most patients had serious complications and a history of body louse exposure, highlighting the need for clinicians to consider housing status and potential lice infestation when diagnosing and treating suspected cases.
A WHO remit to improve global standards for medical products of human origin.
Bull World Health Organ
October 2024
In recent decades, considerable advances have been made in assuring the safety of blood transfusion and organ transplantation. However, with the increasing movement of medical products of human origin across international boundaries, there is a need to enhance global norms and governance. These products, which include blood, organs, tissues, cells, human milk and faecal microbiota, are today crucial for health care but they also pose unique risks due to their human origin, such as disease transmission and graft failure.
View Article and Find Full Text PDFPathogen-Agnostic Advanced Molecular Diagnostic Testing for Difficult-to-Diagnose Clinical Syndromes-Results of an Emerging Infections Network Survey of Frontline US Infectious Disease Clinicians, May 2023.
Preetika S Rao Diane L Downie Corinne David-Ferdon Susan E Beekmann Scott Santibanez Matthew Kuehnert
Open Forum Infect Dis
August 2024
Article Synopsis
- * A survey of 643 infectious disease providers revealed that 74% had used advanced molecular testing recently, with 16S rRNA gene sequencing being the most common method employed.
- * Major barriers to using these tests included the lack of national guidelines and high costs, but there's potential for improvement in clinical practice and public health with better access and clear protocols.