Repair of an iatrogenic lacrimal fistula: a case report.

Lacrimal cutaneous fistula is an uncommon yet clinically significant condition leading to persistent epiphora, recurrent infections, and significant patient discomfort. It can be congenital or acquired. Timely identification and appropriate surgical management are crucial to alleviate symptoms and restore normal lacrimal system functionality.

Cancer-Associated Fibroblasts: Master Tumor Microenvironment Modifiers.

Cancer cells rely on the tumor microenvironment (TME), a composite of non-malignant cells, and extracellular matrix (ECM), for survival, growth, and metastasis. The ECM contributes to the biomechanical properties of the surrounding tissue, in addition to providing signals for tissue development. Cancer-associated fibroblasts (CAFs) are stromal cells in the TME that are integral to cancer progression.