Publications by authors named "M Krajc"
Aim: To evaluate Slovenian adolescents' awareness of common cancer risk and protective factors, identifying knowledge gaps to develop targeted health education initiatives.
Methods: A cross-sectional questionnaire survey was conducted among 795 students aged 13 to 19 years in primary and secondary schools in Slovenia. The responses were analysed using descriptive and analytical statistics.
Deep-learning-based models have achieved state-of-the-art breast cancer risk (BCR) prediction performance. However, these models are highly complex, and the underlying mechanisms of BCR prediction are not fully understood. Key questions include whether these models can detect breast morphologic changes that lead to cancer.
View Article and Find Full Text PDFObjective: In patients with platinum-sensitive relapsed ovarian cancer (PSROC) harboring pathogenic/likely pathogenic variants (PV) in BRCA1 and BRCA2 genes, olaparib maintenance monotherapy (OMT) is a viable option. Our study aimed to evaluate the impact of different BRCA1/2 PV in survival outcomes and safety of OMT in BRCA1/2-mutated PSROC patients, focusing on the type and location of PV.
Methods: We assessed the outcomes of 100 BRCA1/2-mutated PSROC patients treated at our institute, analyzing progression-free survival (PFS) and overall survival (OS).
Article Synopsis
- Genetic alterations play a crucial role in cancer development, highlighting the need for effective genetic counselling to support patient decision-making in EU Member States.
- A study of national legislation across 27 EU countries revealed that 22 have laws on genetic counselling, but practices and regulations differ significantly.
- Common barriers include workforce capacity and genetic literacy, with calls for better integration of genetic counsellors and updated laws to improve the overall practice.