[Fiber endoscopic evaluation of swallowing (FEES) - an important tool for diagnosing myasthenia gravis].

History And Admission Findings:  A 76-year old man was admitted with a globus sensation and weight loss for further investigations to our geriatric ward. A gastroscopic evaluation executed before had been unremarkable.

Investigations:  Physical examination was unremarkable, including a neurological examination.

Medication risks in older patients (70 +) with cancer and their association with therapy-related toxicity.

Background: To evaluate medication-related risks in older patients with cancer and their association with severe toxicity during antineoplastic therapy.

Methods: This is a secondary analysis of two prospective, single-center observational studies which included patients ≥ 70 years with cancer. The patients' medication lists were investigated regarding possible risks: polymedication (defined as the use of ≥ 5 drugs), potentially inappropriate medication (PIM), and relevant potential drug-drug interactions (rPDDI).

[BCG-therapy as a rare reason for postrenal failure].

History And Clinical Findings:  In the following case report, we describe a patient with acute renal failure due to an urinary congestion level II-III under BCG-(Bacillus Calmette-Guérin)-therapy because of bladder cancer. Cystoscopy revealed the diagnosis of BCG-induced intramural narrowing of distal ureters bilaterally.

Therapy And Further Development:  After receiving a double-J-catheter the renal function returned to normal.

[Polycythemia vera as a cause for progressive cognitive impairment].

History: A 82-years old woman was admitted with a progressive cognitive decline for further investigations and treatment.

Findings And Diagnosis: In the computed tomography of the brain findings of subcortical artherosclerotic encephalopathy (SAE) were present. Laboratory findings revealed elevated hemoglobin-levels (19.

Comparing the performance of the CARG and the CRASH score for predicting toxicity in older patients with cancer.

Objectives: To compare the CARG (Cancer and Aging Research Group) and CRASH (Chemotherapy Risk Assessment Scale for High-Age Patients) score regarding the predictive performance for severe toxicity in older patients with cancer.

Methods: We recruited patients ≥70 years and applied the CARG and CRASH score before the start of systemic cancer treatment. The CARG predicts severe overall toxicity; the CRASH additionally predicts hematologic and nonhematologic toxicity.